RotaPrep Homogenizers

HyperLysing for Any Workflow

From high-throughput benchtop processing to portable field homogenization, RotaPrep offers three powerful systems engineered for fast, consistent, and efficient sample preparation.

  • MegaLyser — High-throughput benchtop processing
  • PolyLyser — Parallel multi-sample processing
  • MonoLyser — Portable field and laboratory homogenization
RotaPrep MegaLyser, PolyLyser, and MonoLyser homogenizer systems

Choose Your System

Choose the Right Homogenizer for Your Workflow

From high-throughput processing to portable sample preparation, RotaPrep offers a homogenizer for every workflow.

RotaPrep MegaLyser homogenizer

MegaLyser

High-throughput lysis system for 96-well plates, 2 mL, 15 mL, or 50 mL samples with ultrafast sample lysis.

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RotaPrep PolyLyser homogenizer

PolyLyser

Programmable processing for 2 mL, 15 mL, or 50 mL tubes, at room temperature or with dry ice.

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RotaPrep MonoLyser portable homogenizer

MonoLyser

Portable ultrafast sample preparation for two standard 2 mL tubes in the field or laboratory.

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Versatile Sample Preparation

Built for a Wide Range of Applications

RotaPrep homogenizers support demanding sample preparation workflows across research, biotechnology, environmental testing, agriculture, and more.

Application Typical Samples Workflow Need
DNA & RNA Extraction Cells, tissues, and microbial samples Fast nucleic-acid preparation
Microbial Disruption Bacteria, yeast, and fungal spores Tough cell-wall disruption
Metagenomics Soil and fecal samples Complex-sample homogenization
Plant & Agricultural Leaves, seeds, cereals, and crops Fibrous and hard samples
Tissue Processing Soft and tough animal tissues Reproducible sample recovery
Environmental Testing Water, filters, and environmental samples Field or high-throughput prep

System Comparison

Compare RotaPrep Homogenizers

Compare throughput, sample capacity, tube formats, processing environment, technology, and portability.

Swipe left or right to compare all three instruments.

FIND YOUR
SYSTEM

Three instruments.
One clear
comparison.

MegaLyser instrument

MegaLyser

PolyLyser instrument

PolyLyser

MonoLyser instrument

MonoLyser

Best forHigh throughputParallel processingPortable processing
Sample capacity96-well plates12 × 2 mL / 2 × 15 mL / 2 × 50 mL2 × 2 mL
Tube formats2 / 15 / 50 mL2 / 15 / 50 mL2 mL
EnvironmentLaboratoryCryogenic /
room temperature
Lab / field
Technology /
performance
HyperLysingHyperLysingUltrafast
PortabilityBenchtopBenchtopHandheld

Find Your System

Ready to Find the Right Homogenizer?

Whether you need high-throughput processing, parallel sample preparation, or portable homogenization, RotaPrep has a system built for your workflow.

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