ROTAPREP SAMPLE PREPARATION

Lysing Matrix Tubes & Bulk

Premium Performance. Flexible Formats. Better Value.

Ready-to-use lysing matrix tubes and bulk grinding media engineered for efficient, consistent sample disruption across molecular biology, genomics, biotechnology and research workflows

✓ Ready-to-use lettered lysing matrix tubes

✓ Bulk beads and grinding media for flexible workflows

✓ Compatible with RotaPrep and other bead-beating systems

Shop Lysing Matrix Tubes → Shop Lysing Bulk Media →

WHY ROTAPREP LYSING MATRIX

Suitable for Protocols Using Standard Lettered Lysing Tubes

Premium lysing matrices designed for consistent performance across a wide range of sample types and workflows

RotaPrep offers a full line of the standard lettered lysing tubes, that can be used for any molecular biology, genomics or bioanalytical applications. These are shown below.

These tubes are suitable for any lettered tube referenced in any literature. The formulations are identical, and our tubes are prepared in aseptic conditions in order to give the most optimum lysing results.
These tubes can be used with RotaPrep homogenizers and the bead-beating instruments listed in the Instrument Compatibility table below. RotaPrep’s HyperLysing technology supports efficient sample disruption.
The tubes are compatible with any existing buffer systems or kits, and are ideal for any unique buffers or sample preparation kits prepared one might prepare inhouse.

Due to our business model and that we prepare our tubes inhouse, we are able to offer a lower price than can be found from other sources. This is a savings that can be enjoyed by the end user without any sacrifice for quality. In fact, in our preparation process, we take great care to make sure these tubes are prepared with the highest quality possible.

WHY ROTAPREP

Built for Consistent Sample Preparation

RotaPrep offers a complete line of standard lettered lysing tubes for molecular biology, genomics, DNA and RNA extraction, and advanced bioanalytical applications. Our precision-formulated lysing matrices are optimized for efficient mechanical cell lysis and bead beating, delivering high-yield nucleic acid and protein extraction from bacteria, tissue, plant, and environmental samples while supporting use with compatible bead beaters, buffer systems, and extraction kits for reproducible, high-performance sample preparation.

✓ Multiple Matrix Options

Choose from different bead materials, sizes and combinations to match your sample type and workflow

✓ Flexible Laboratory Workflows

Available in convenient pre-filled tubes or bulk media for laboratories requiring greater preparation flexibility

✓ Designed for Reproducibility

consistent matrix configurations help support repeatable sample preparation from run to run

Instrument Compatibility

RotaPrep 2 mL lysing matrix tubes, including Lysing Matrix A and our other 2 mL matrix options, can be used with the following MP Biomedicals FastPrep and Omni Bead Ruptor homogenizers.

Manufacturer	Compatible instruments
MP Biomedicals	FastPrep-24 Classic FastPrep-24 5G FastPrep-96 Super FastPrep-2
Omni	Bead Ruptor 4 Bead Ruptor 12 Bead Ruptor 24 Bead Ruptor Elite

Compatibility applies to RotaPrep 2 mL lysing matrix tubes used with the appropriate 2 mL tube holder or adapter for the instrument.

Other Names for Lysing Matrix Tubes

Lysing matrix tubes are also commonly described as bead beating tubes, bead lysis tubes, homogenization tubes, or prefilled bead tubes. These terms describe tubes containing beads or grinding media for mechanical sample disruption and cell lysis.

Supplier terminology varies: Omni describes its products as bead beating tubes and bead-lysis kits; Zymo Research offers ZR BashingBead Lysis Tubes; Bertin offers Precellys Lysing Kits; and Benchmark Scientific offers prefilled tube kits for bead homogenization.

RotaPrep offers a range of 2 mL lysing matrix tubes for different sample types. Choose the bead material and size suited to your sample, and use the instrument compatibility table above to check supported equipment. These names describe related product categories; bead formulations and instrument compatibility vary by product.