ROTAPREP SAMPLE PREPARATION
MegaLyser
High-capacity homogenization with HyperLysing technology
Prepare samples in 96-deep-well plates or multiple tube formats with full-length bead travel and adjustable processing conditions.
- Supports 96-deep-well plates and 2 mL, 15 mL, and 50 mL tubes
- Full-length bead motion for efficient sample disruption
- Adjustable speed and run time with touchscreen control
- Designed for molecular biology, metagenomics, and environmental workflows
How the MegaLyser Works
The MegaLyser uses HyperLysing motion to drive grinding balls and lysing matrices through the full length of the sample tube. Its rotational pathway allows the grinding media to travel from one end to the other with each revolution, promoting efficient mechanical disruption.
User-controlled settings and closed-loop feedback let you tailor the processing conditions to your samples. The adjustable speed range is 10–30 revolutions per second, with a run-time range of 1–60 seconds.
The original product information reports plant-material homogenization after 10 seconds at 30 revolutions per second. Processing time depends on the material, tube format, grinding media, and intended downstream workflow.
Learn about RotaPrep’s HyperLysing technology →Applications and Sample Types
Sample Types
- Plant tissue, seeds, and cereals
- Animal tissue and other biological materials
- Bacteria, yeast, and fungal spores
- Soil, fecal, water, and environmental samples
Application Areas
- DNA and RNA extraction
- Microbial disruption, including yeast, bacteria, and fungal spores
- Soil and fecal metagenomic sample preparation
- Plant tissue homogenization
- Seed, cereal, and agricultural sample lysis
- Tissue processing
- Environmental and water sample preparation
- High-throughput screening workflows
Downstream Workflows
Prepare samples for DNA, RNA, protein, and small-molecule extraction. Select processing conditions and an appropriate purification procedure for your material and analytical method.
Built for Flexible Sample Preparation
Multiple Formats
Use a 96-deep-well plate or select a tube adapter for 2 mL, 15 mL, or 50 mL tubes.
Controlled Processing
Adjust speed and run time for the sample, using touchscreen controls and closed-loop feedback.
Benchtop Throughput
Process multiple samples in academic laboratories, biotechnology facilities, and agricultural or environmental testing workflows.
Simple to Use
Select Your Format
Choose a compatible plate or tube format, the matching adapter, and grinding media appropriate for your sample.
Set Processing Conditions
Load and secure samples according to the operating instructions. Use the touchscreen to select the speed and run time for your protocol.
Continue Your Workflow
After homogenization, proceed with the extraction, purification, or analysis procedure appropriate for your sample.
Sample Formats and Capacity
| 96-deep-well plate | 1 plate |
|---|---|
| 2 mL tubes | 24 tubes |
| 15 mL tubes | 12 tubes |
| 50 mL tubes | 4 tubes |
Use the adapter specified for your plate or tube format. Tube adapters are sold separately.
Technical Specifications
| Product code | RP-ML-01 |
|---|---|
| Lysing technology | HyperLysing full-length bead motion |
| Speed range | 10–30 revolutions/second (600–1,800 RPM) |
| Run-time range | 1–60 seconds |
| Load capacity | 1.1 lb (0.5 kg) |
| Dimensions (L × W × H) | 18.5 × 17.5 × 14 inches |
| Weight | 45 lb |
| Power options | 115 VAC / 60 Hz, 6 A; 230 VAC / 50 Hz, 3 A |
| Controls | Touchscreen with closed-loop feedback |
MegaLyser Resources
Browse product pictures, ordering information, and detailed product specifications.
MegaLyser Product Gallery
Ordering Information
Catalog number: RP-ML-01
The product package listed on the original page includes the MegaLyser instrument, a 96-well plate adapter, a power cable, and a manual. Adapters for 2 mL, 15 mL, and 50 mL tubes are sold separately.
Confirm the plate or tube format and required adapters when ordering.
View Pricing / OrderOperating Instructions and Protocol Support
Contact RotaPrep for operating instructions, adapter compatibility, or help planning your sample-preparation workflow.
MegaLyser Product Details
High-capacity bead beating for 96-deep-well plates and 2 mL, 15 mL, and 50 mL tube formats.
Processing and Control
- Full-length bead travel: HyperLysing motion drives grinding media from one end of the sample tube to the other.
- Adjustable processing: Touchscreen settings and closed-loop feedback support sample-specific speed and run-time selection.
- Flexible workflows: Prepare plant, tissue, microbial, soil, fecal, and environmental samples for downstream extraction and analysis.
Plant-material example: complete homogenization after 10 seconds at 30 revolutions per second. Optimize conditions for the sample, grinding media, and intended analysis.
Supported Formats and Capacity
| Sample format | Capacity per run |
|---|---|
| 96-deep-well plate | 1 plate |
| 2 mL tubes | 24 tubes |
| 15 mL tubes | 12 tubes |
| 50 mL tubes | 4 tubes |
Use the matching adapter for each format. Tube adapters are sold separately.
Instrument Specifications
| Product | MegaLyser High-Capacity Bead Beater |
|---|---|
| Catalog number / SKU | RP-ML-01 |
| Brand | RotaPrep Inc. |
| Speed range | 10–30 revolutions per second (600–1,800 RPM) |
| Run-time range | 1–60 seconds |
| Load capacity | 1.1 lb (0.5 kg) |
| Dimensions (L × W × H) | 18.5 × 17.5 × 14 inches |
| Instrument weight | 45 lb |
| Power options | 115 VAC / 60 Hz, 6 A 230 VAC / 50 Hz, 3 A |
| Controls | Touchscreen with closed-loop feedback |
Included in the Package
- MegaLyser instrument
- 96-well plate adapter
- Power cable
- Manual
Sold separately: Adapters for 2 mL, 15 mL, and 50 mL tubes.
Ordering Details
Catalog number: RP-ML-01
$16,000.00
Pre-order the MegaLyser. Confirm the plate or tube format and required adapters when ordering.
View Pricing / Order