What is HyperLysis?
HyperLysis™ is the World's fastest bead beating based sample homogenization technology. RotaPrep invented a new way for scientists to homogenize, lyse, and grind biological samples, unlocking DNA, RNA, and proteins with speed and comfort. It is designed for anyone looking to raise practicality, consistency, and results in genomics, proteomics, or molecular biology.
For years, people relied on bead-beating tools that rocked and jostled tubes in short, repetitive motions. These traditional machines could only move the beads a tiny distance, never reaching the ends of the vessel. That left parts of the sample untouched, slowed the entire workflow, and sometimes let heat sneak into the process. Anyone searching for better sample homogenizer techniques or hunting for a lyser or grinder knows the struggle. Are the results reliable enough? Was all the DNA, RNA, and protein extracted? Is temperature control an issue?
RotaPrep asked whether it was possible to push the beads further, to cover the whole length of every tube. That simple idea reshaped the science. Instead of short repetitions, HyperLysis gives every tube a smooth circular journey. As the tube moves, the beads sweep from one tip to the other, touching all areas and leaving no sample ignored. Each circle sends energy gently and evenly through the lysing matrix, so the grinding action stays consistent inside and out.
HyperLysis in Action
Whether your laboratory is working on DNA sequencing, protein purification, or any other biological study, HyperLysis makes the whole process easier and more dependable. You get complete extraction in seconds, even when working with fragile samples or tough matrices. RotaPrep’s MonoLyser, PolyLyser, and MegaLyser models use the same gentle, full-length circular motion, making them ideal for personal research as well as high-throughput workflows. You can expect cooler samples and reliable reproducibility with every run.
This is not just a step forward. HyperLysis offers a new scientific approach that turns routine sample grinding into a more effective, enjoyable experience. RotaPrep’s patent-backed platform transforms the way scientists handle their samples, offering greater speed, comfort, and precision than ever before.
Curious about how easy science can feel? Try HyperLysis and discover a new level of control in homogenizers, lysis, and sample preparation. RotaPrep invites you to experience innovation from the ground up.